The U.S. FDA is likely to approve am anti-aging drug for dogs that may prolong the lives of large-breed dogs.
According to a last week statement of a San Francisco biotech Loyal company, the company who produces the drug.
Currently, the FDA has not approved any animal drugs for this purpose.
Key Points of Anti-aging Drug for Dogs
- An anti-aging drug awaits FDA approval, specifically designed for dogs.
- Game Changer News: The drug, awaiting approval, could revolutionize extending the lifespan of man’s best friend.
- Paws for Approval: The drug by Loyal for Dogs has cleared the first of three FDA hurdles.
- Aging Intervention: Administered every few months to dogs over seven, it aims to extend their healthy years.
- Market Outlook: Projected to be affordable, the drug might hit the market by 2026.
- Not Just for Dog Owners: Even if you don’t have a dog, this breakthrough matters.
- Human Implications: Success in dogs may pave the way for similar anti-aging drugs for humans.
- Connecting Lifespan Dots: If successful, this would mark the first FDA-approved anti-aging drug.
- Hopeful Horizon: The goal is to extend both canine and potentially human lifespans.
There are 25 million large-breed dogs in the US alone – these are 25 million dogs to help them live longer and with better quality of life”, said Celine Halioua, CEO and founder of Loyal, in a statement sent to Fox News Digital.
The company claims that LOY-001 could decrease aging-associated procedures for dogs, who exceed 40 pounds.
The medication binds to a protein hormone commonly known as IGF-1 which increases the aging process. A Loyal spokesperson claims that it is meant to block age-related canine diseases, not symptoms. Are you enjoying the Anti-aging Drug for Dogs news? Please let us know.
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Anti-aging drug for dogs from San Francisco firm moves closer to gaining FDA approval https://t.co/FCwJI90lyE
— Fox News (@FoxNews) December 10, 2023
“Loyal’s approach is a different paradigm and using what we understand about the mechanisms of ageing to reduce risks of these diseases in the first place,” said the company in a release to Fox News Digital.
Last week, the drug maker indicated that LOY-001 had hurdled some early hurdles with the FDA, which signified that the data indicated that the drug worked up to now.
However, to completely approve the drug and have it on its way to the market, more milestones must be reached.
It consists of the completion of a big clinical trial and a safety review, as well as a review of manufacturing data.
To date, the four-year process has involved interventional trials of LOY-001 in an FDA-accepted model of canine aging and observational (no-drug) study of 451 dogs according to Loyal’s website.
The company added that “today’s milestone is an important step in Loyal’s conditional approval application”.
The statement continued that it means the FDA agrees that LOY-001 has a reasonable expectation of effectiveness. Once the FDA approves Loyal’s manufacturing and safety data packages, Loyal can market the drug for lifespan extension in the targeted canine population.
Approval for conditional use is given for up to five years, during that time Loyal will provide the missing effectiveness data and apply for final approval.
Fox News Digital had consulted a veterinarian who said that an average dog lives for 10 to 13 years – for larger breeds, life can be even shorter. Are you enjoying the Anti-aging Drug for Dogs news? Please let us know.
It is believed that this is a case of selective breeding which enhances the size and development of the dog. Dr. Ivana Crnec, a veterinarian with Texas-based Veterinarians.org told Fox News Digital that size and growth rate are some of the main factors that influence the lifespan of a dog.
Large dogs exhibit much higher amounts of the growth-promoting hormone IGF-1 — which is believed to accelerate aging and reduce lifespan — compared to small breed dogs.
This hormone promotes growth thus, the new experimental drug reduces its levels.
Crnec asserted that the drug was path-breaking in his professional opinion.
She concluded by stating that “it is safe to say that LOY-001 is promising despite having to wait and assess its side effects and results.” The fact that the FDA called this drug having ‘reasonable expectation of effectiveness’ is a great statement on its potential. (She was not involved in the research.)Crnec told Fox News Digital, “The drug will indirectly help to improve the life quality of large and giant dog breed.
Other vets were cautiously optimistic. Are you enjoying the Anti-aging Drug for Dogs news? Please let us know.
“It sounds too good to be true,“ observed Dr. Jeffrey Krasnoff, a vet at Brookville Animal Hospital on Long Island, to Fox News Digital about the experimental drug.
Oh wow, what a great research would it be? It should really improve the lifetime of our big, friendly dogs.
A veterinarian gives one injection for this drug at three to six months intervals, but the company is working on one pill for daily intake as stated on Loyal’s website.
The availability of LOY-001 is set for 2026, upon receiving approval from FDA on Loyal’s manufacturing and safety data.